Understanding the Mechanism of Action of Zerodol SP

Zerodol SP

Zerodol SP Tablet is a pain reliever tablet which is used to reduce pain and inflammation in musculoskeletal conditions such as rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis and orthopedic pains. You may take one tablet orally twice a day. The dosage may vary based on your medical condition, severity of pain, and overall health. However, it’s crucial to adhere to the prescribed dosage, take them for short duration and not exceed the dosage to avoid adverse effects of painkillers. 

If you take an excess of Zerodol SP Tablet in a day, you may experience headaches, nausea, vomiting, and stomach pain. In that case, do not delay seeking medical assistance, even if symptoms seem mild initially.

Please consult your doctor before taking Zerodol SP Tablet as these tablets are intended for use in these specific conditions only.

What are the uses of Zerodol SP Tablet?

Zerodol SP Tablet is used in the following conditions: 

  • Musculoskeletal disorders: Zerodol SP tablets effectively alleviates pain and inflammation in diverse musculoskeletal conditions like rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis.
  • Other orthopedic conditions: This tablet provides relief from pain and inflammation linked to orthopedic issues, infections, trauma, and various surgical procedures.

How Does Zerodol SP Tablet work?

Zerodol SP Tablet combines three active ingredients: 

  • Paracetamol/Acetaminophen (325 mg): It is an analgesic (pain-relieving) and antipyretic (fever-reducing). It helps manage pain and reduce fever.
  • Aceclofenac (100 mg): It belongs to the class of non-steroidal anti-inflammatory drugs (NSAIDs). It works by inhibiting an enzyme called cyclooxygenase (COX), which is involved in the production of prostaglandins, which cause inflammation, pain, and fever. By blocking COX and reducing prostaglandin levels, aceclofenac helps alleviate pain and inflammation.
  • Serratiopeptidase (15 mg): It is an anti-inflammatory agent. It works by breaking down fibrin, which helps reduce inflammation and swelling. It also deactivates bradykinin, a substance that causes inflammation.

What Are the Safety Precautions When Using Zerodol SP Tablets?

Follow these safety precautions for the optimal effectiveness of this tablet:

  • Use in Children: Zerodol SP Tablet is not intended for children. Consult your doctor for other safer options.
  • Asthma: Do not take this tablet if you have asthma. It may worsen the existing condition. 
  • Pregnancy and breast-feeding: Zerodol SP Tablet is not recommended for use during the initial two trimesters of pregnancy unless its benefits significantly outweigh potential risks to the fetus. These tablets are strictly not recommended in the third trimester of pregnancy. This tablet contains aceclofenac, a NSAIDs. If this tablet is used in the final trimester, it might cause complications at the time of delivery. If you are a breastfeeding mother, use this tablet with caution. It can be excreted in breast milk. 
  • Fertility: This tablet may affect female fertility and is not advised for women trying to get pregnant. If you are facing challenges in conceiving or are undergoing fertility issues, stop using this tablet or use it only after consulting your doctor.
  • Use in Elderly Patients: Elderly patients with heart, kidney and liver impairment should exercise caution when taking this tablet. Discuss your medication and medical condition with your doctor before taking this tablet.
  • Peptic Ulcer/Bleeding Disorders: This tablet is not recommended to be used of you have active or recurrent peptic ulcer, bleeding or bleeding disorders.
  • Gastrointestinal Bleeding or Perforation: This tablet is not intended for individuals with a history of GI bleeding or perforation related to previous NSAID therapy.
  • Heart Conditions: Do not use this tablet if you have a severe heart problem.
  • Acute Porphyria: Zerodol SP Tablet is not recommended in individuals with acute porphyria, a group of rare genetic disorders affecting the nervous system and skin. The use of this medication may exacerbate symptoms or complications associated with acute porphyria.
  • Kidney Impairment: Zerodol SP Tablet is not recommended in cases of severe kidney impairment. 
  • Liver Impairment: Zerodol SP Tablet is contraindicated in individuals with active liver disease or hepatitis. Furthermore, its use is not recommended in cases of severe liver impairment. Caution is warranted, and the tablet should be used cautiously, if at all, in individuals with a history of liver disease.
  • Driving and using machines: This tablet may cause dizziness, vertigo, drowsiness, fatigue, and visual disturbances. Refrain from driving or operating machinery after taking this tablet.
  • Alcohol restrictions: Avoid alcohol consumption, as it may increase the risk of gastrointestinal side effects and liver damage.

What Medicines Should You Avoid When Taking Zerodol SP Tablet?

Avoid taking medications to treat heart failure, antihypertensive medications, oral antidiabetics, chemotherapy and immunosuppressants, diuretics, anticoagulants, medications to induce abortion (mifepristone), corticosteroids, and quinolone antibiotics. Also, refrain from taking acid reflux medications, cholesterol-lowering medications such as (cholestyramine), anticoagulants, antibiotics (chloramphenicol), anticonvulsants, and antituberculosis medications (isoniazid). These medications may affect the safety, effectiveness and absorption of Zerodol SP Tablet. You can easily procure Zerodol SP from trusted online medicine websites.